Change Database: Show Menu  Hide Menu
  See Titles        See Abstract        See Only Verified Posts       

Health Optimization Methodology for Longevity and Health

Total Posts: 16
      
Click field name below to sort records.
  1 2 3 4 5 6 7 8 9
Sys_record_id Subject Login Lastname Firstname Date Content filename App
 
1
2
The Critical Effects of Exercise Times
3 4 5
6
7
In the mainstream medicine, no body would believe that exercise timing is important. The reason is that it uses a population-based approach. By using this approach, it is impossible to study the effects of exercise timing on health.

Since 2001, I have started advocating personalized medicine. More specifically, I have established a new medicine known as Health Optimization Engineering. Based on the principle I developed, I will show that exercise timings have decisive impacts on running a successful healing program.

There are at least tens to hundreds variables I must consider in deciding what is the best for an individual person. However, I will consider only two of the most important variables that impact every person: the level of metabolic products in local tissues, and hydration condition in sleep time. 

In order to consider those impacts, you must consider how your body's condition affects your ability to do exercises. 

In the morning, you have gained a full recovery from a prior day of work. Your body metabolic by-products are at the lowest. Thus, this is time you can do more exercise. If you try, you can quickly adjust your body to do more endurable exercises. If you can do half an hour exercise in the afternoon, you could double the amount of exercise in the morning. That is why virtually most martial art teaching books recommends that morning is the best time for doing exercises. Although ancient people could not prove, they figured this out by experience.

One huge advantage in the morning is the body is the best time for switching from glucose-use metabolism path to fatty acid burning path. You last meaning is more than 10 hours away, when you get up, your glucose level in the blood is lower. This is the easiest time to turn on fatty acid  path way to use fats stored in the body. After spending some time to get used to this, you will find you will not feel fatigue from doing exercise: you have well restored body and have huge amount fats to be used. Naturally, it is the best time to burn fats to restore the vascular system.

From 12 to 2 PM each day, you should avoid doing intensive physical exercise. Since, the morning exercise has resulted in local tissue fatigues and generated too much toxic by-products,  doing more is no longer good. However, it is a great time to do low-impact mind-training exercises such as meditation, deep breath, and even a nap. Such exercise can help you restore the fatigue from your morning exercise. If you must do more exercises, make sure that you will avoid doing the same exercise what will use the same muscles. The adverse impacts of metabolic by-products are mainly limited to the local issues. This is due to how blood stream contact tissue cells. If your hip joints are used for a long time in the morning, you should avoid using them too much. Instead, you should use more of your upper body and hands. So, a well load-balanced exercise will help you prevent local tissues from being damaged by excessively higher levels of metabolic by-products.

If you have compromised kidneys or you want to have the body to run at low levels of toxic metabolic products, you might take a nap, doing meditation, or doing low-impact and gentle exercises. If you are able to enter into a tranquility state, you will soon notice how the exercises can help recharge your energy: it really helps your body to reduce metabolic by-products production and thus allows your body to clear up the toxic by-products. This practice can help your body maintain lowest levels of metabolic by-products and thus must be very beneficial to health and longevity.

If you must do more physical exercise to maintain body weight, you should considering doing it from 2-5 PM. The time should be chosen so that your body metabolic by-products are reasonably low and that you will finish your exercise long before your sleep time. If you do not do exercise in the morning, you may do more at a large time window in this time window. If you have done morning exercise, you should sense how you feel. If you are really tired, you should avoid doing too much, reducing the duration, or doing more gentle type of exercise. The idea is that you should avoid produce too high levels of acid, ammonia, and other toxic by-products.  Persistent exposure to high levels of by-products can hurt your health in a long run. You will be unable to tell from one time, twice or several times exposure. Harmful impacts result from long run exercises.

What is the latest time can you do exercise? This will depend upon how well your body can clear up toxic metabolic by-products. If you do intensive exercises before going to bad, your body would generate high levels of metabolic by-products. If you do not drink enough water, the by-products can hurt you very badly. To save your kidneys, you could have to drink more water, that will force you to get up to urinate at night. If you keep doing it, your will develop a bad sleep pattern. Your brain remembers this cycle, and always wakes up. The last exercise should be finished at least several hours before your sleep time.  This will ensure that you have enough time to clear up metabolic by-products.

If your kidneys are not good, you should use gentles, leg-dominant, and mind-focus exercises. Those exercises will help your body lower your body's metabolic by-products before you go to bed. This will help you reach the lowest level metabolic by-products. With time passing, your kidneys will improve their functions. Improved kidney functions will help your whole body improve your whole body health conditions.

My analysis is originally based upon Chinese Medicine. However, it is entirely consistent with all medical facts: as long as you focus on your body, those things become obvious.

By using health optimization principles that Dr. Zha and I have developed, you can gradually improve your health conditions. In Chinese Medicine,  healing focus is blood, Qi and Yu (retained toxic matter in a broader sense). This brief exercise scheme could easily improve your vascular system. It must improve Qi level in the body. By focusing on removing toxic by-products, it also helps you improve Qi (life energy). When Qi high, it can alter stem cells differentiation behaviors so that they will produce healthier and better tissue cells in the locality of the body. That is why exercises are an extremely powerful mean for achieving health and longevity. 

It is well known that exercises were used as the primary healing means in multiple cultures such as India, China, Japan, and most East Asian nations. It was never coincidental. Exercises were so recognized as the best healer because they worked absolutely. However, they were rejected by modern medicine because it uses a population-based model, FDA double-blind controlled trial drug approval protocol, and mental steps doctrine in the patent law. Those three flawed concepts, which can be traced to absurd concepts used in common law courts, have precluded research, invention, and commercial activities in any aspect of exercises. Thus, most exercises are now used to deliver only a fraction of potential health benefits. 

As a result of the precluding impacts of three legal concepts, no study has ever been done to look into any of six key elements: relaxation, deep breath, focus, induction sound induction, action mode (only only things modern research might tough is calories burning effect). They directly resulted in junk medicine and an incurable era. I am collecting massive data in igoosa.com online database to repudiate the incurable concept.  The ancient people have left us with wealthy teachings in each of those elements by experiences. The experiences-based teachings can easily cure nearly all chronic diseases for those who have willpower.
8
9
 
1
2
A Personalized Approach to Determining Optimum Sleep Time
3 4 5
6
7
Sleep duration has been an important health subject for years, now most sources suggest that the best sleep duration is 7.5 hours, and too little and too much sleep can increase death rates. Those studies might serve as good guidance to government in planning its resources, their conclusions, if they are used as health guidance, are wrong. Even the question is improper. It most probably will hurt whoever tries to follow.

For political purpose, governments need to treat people by categories in order to impose same rules and regulations. Such rules and regulations are arbitrary. However, when a single rule is used as health-care guidance, the validity of the population data would depend upon two assumptions: all human beings are same and sleep is the limiting and independent factor that affects health and death rate. None of those two assumptions can hold. First, among people in a population, there are young people, women and men, and old people. Within each category, people may be vegetarians, caffeine drinkers, alcohol users, or drug addicts. People have different jobs such as physical workers, sedative workers, and high stress workers. Their health conditions range from very healthy to very poor. All those factors affect death rates. So, the conclusion form such data cannot make a slightest sense.

The differences in those factors are far more than the difference we see from wheat grown in a farm. They are more different from the differences in TV brands, TV models, and different use conditions like broken, refurbished, and new units. When the population data is acquired from commingled subjects and is turned into some sort of ?average?, the conclusion is useless to every person. There is no such average person in reality.

The second fatal flaw in those studies is that sleep duration is not a limiting independent factor among a large number of other factors. It is not an important factor in many deaths. People might die from all kinds of causes that are influenced by sleep duration. Thus, true contributory factors to death rates cannot be attributed to sleep duration in a fixed way. Even though, researchers in every field must consider limiting factors and how a factor interacts with other factors, but this practice has often been ignored in medical research. When sleep duration is not a limiting factor, one cannot ignore other limiting factors and other interactive factors in assessing true effects of sleep duration. The conclusion is naturally flawed.

We must use the optimization method for complex life system to analyze how sleep duration affects health, daily function, and lifespan. It must be analyzed by looking at its interactions with a large number of other factors. First, we need to understand what is the function of sleep? It is generally agreed that sleep is a process for recovery of energy,  clearing metabolic by-products, and repairing the body. One would expect that the more the better. However, excessive sleep would reduce the time for the body to do physical activities and exercise and thus result in fat accumulations. Thus, excessive sleep would result in obesity and slowly damage the vascular system. Thus, I can easily see that there is a optimum point for each person and this point must depend upon individual person's overall activities, lifestyle, health condition, age, and development stage. Sometimes, a change in any of those main parameters would require an adjustment to the sleep duration. For example, if your change in jobs may require you to do more complex mental work, you may need more sleep to gain full recovery from the fatigue each day. 

The speeds of recovering and repairing the body are highly depend upon the vascular condition. The body provides nutrients to tissues in the whole body by convection and diffusion, and bring metabolic products from tissues including the brain, the heart and kidneys by the circulating blood. After you have worked for a whole day, you will feel tired because acids, toxic metabolic products are accumulated in tissues all the body including the brain, the heart, and the kidneys. All toxic substances are brought by circulating blood to the kidneys and were eliminated by the kidneys. If your body can eliminated them completely, you will feel full recovery. The efficiency for eliminating them would depend upon micro-vascular network system and may be limited by your kidney functions. So, some people with kidney diseases often feel tired because their kidneys would not remove toxic substance completely and timely. 

The micro-vascular network conditions can vary by great extent. A good micro-vascular system is that the issue has high density (more capillary number per cross section area) and all capillaries have decent cross section reason (without fat coatings insides), and shorten paths. In contract, a bad micro vascular system is low capillary density, reduced cross-section areas and elongated paths. All those those features might appear minor in terms of numbers, their impacts on the body ability to clear toxic substances can be huge. This has a lot to do with fundamental law of diffusion. When the number of capillaries are fewer, the blood must diffuse a longer distance to reach those terminal cells in any tissues. Unfortunately, diffusion is very slow process. Thus, people with poor health could need longer time to clear toxic substances because the diffusion path is longer and capillaries are smaller. 

This difference in the micro-vascular network explain why some people take little sleep but still feel very energetic while others might feel that they would not get enough sleep and always feel tired. For this reason, one needs not to worry about following a definite sleep duration. What is important is you must make sure that you will get enough sleep to make sure that you can get fully recovery. Getting ten hours sleep does not mean better than getting 6 hours sleep. 
We should note that the sedative lifestyle is a very important factor that affects sleep duration. 
For people with sedative lifestyle, critical issues are low consumption of energy, monotonic activities, excessive accumulation of fats. Due to physical inaction, the body is conditioned to use more energy in glucose and with less activity of using fatty acids. This could favor fat accumulation insider the capillaries. If calories are not balanced, a long-term sedative lifestyle will slowly compromise the micro-vascular network. The subjective signs are people have poor energy, easily get fatigue from physical work, can feel short breath for doing minor physical activities. In this stage, all physical checks will be normal. However, it is very bad to health. It is easy to fix and reverse for a long time. Most people have decades of time to fix.

Sedative people do not have much metabolic waste in the whole body due to limited physical activities. They can gain recovery without much sleep. If they do extraordinary physical activities, they will not be able to recover for days. Therefore, the most critical factor is not the sleep length for repairing the body, but the blood circulation condition in tissues around the body. Taking additional sleep will make the terminal blood circulation worse. Anything that can increase blood circulation and capillary number will have more beneficial affects. We assume that the population data may be applicable to U.S. residents because the population has a high number of overweight and inactive people. However, for people who are active in sports and physical activities, their critical issue is to get rid of metabolic products and repair wears and tears. Getting additional sleep is most probably beneficial to them.

Optimum sleep duration depends upon a large number of factors such as lifestyle, age, job nature, geographic location, weather condition, social activities, sleep quality, and personal health condition. In conducting analysis, one must consider how sleep duration affects the immune system, the digestive system, and energy balance in light of the individual person (but not the population). On one hand, sleep duration must be sufficiently long to have metabolic products fully cleared and have the body fully repaired. On the other hand, it should not be too long to promote more fat deposits to impair the micro-vascular system. Saved energy from one additional hour could be enough to cause a total destruction of health even though it exerts the effect slowly. 

The optimum sleep duration is a dynamic parameter. We should never seek a magic constant that is good for everyone or good for all days in a year. For example, if a person has worked for a long day with massive toxic metabolic compounds in the body, he needs to get more sleep to gain a full recovery. If the person has cancer, a critical goal is to boost the immune system to protect vital organs. More sleep may help, provided that it would not result in further damages by energy imbalance. If a person who tends to eat more than he would need, an excessive sleep will be more damaging; people who can properly balance energy intake may take a longer sleep; people with highly complex mental activities (but without excessive energy intake) may take a longer sleep without worrying about obesity. More sleep may help the person reactivate the immune system, but must learn to prevent the body get overweight.

Optimum sleep duration can be viewed as a function of a large number of factors that interact with each other. Sometimes, a change in one single factor can change the optimum sleep duration.
8 on-sleep-v100.pdf
9
 
1
2
Mental Diseases Will Engulf the U.S. Economy.
3 4 5
6
7
There is a very definitely trend that mental diseases will be a national epidermic which will consume a huge part of the GDP.  Why?

The root reason is the social media based lifestyle. I will show how this lifestyle can cause mental diseases. I find the following four reasons.

The most important reason is an increased sedative life style. When people do less and less physical exercises by spending more time on cell phones, ipot, and mobile computers, they will have degraded vascular systems. Thus, this lifestyle will adversely affect all blood vessels and all capillaries in the heart, the brain, and all organs. Thus, no matter what is impaired, a direct, indirect and consequential effects is degrading blood circulation in the brain. When the brain cells and neurons could not get enough nutrition, all functions in keeping memory, interpreting signals, controlling body will be compromised. This would lead to all mental diseases that could be caused by poor vascular performance. Even poor heart performance can slowly damage brain functions.

The second reason is that when people spend less time in interacting with other human beings, and spend more time on social media, they will lose the ability to deal with and interact with human beings. So, it is expected that future people will lose certain basic skills. When people interact with others in very low frequencies, certain neutrons will not work, lose functions or degrade. This will lead to increased chances of getting depression, mania, and perhaps all kinds of other mental diseases.

The third reason is the harmful effects of the posture of using mobile devices such as cell phones. Whenever people use cell phones doing anything, they tend to bend their necks. Bending the neck in one time or several times with short duration is harmless. However, when a person keeps taking this posture from time to time with the accumulated time being very long, it can damage the neck, the spinal cord and all tissue around the neck. This habit reduces activity level of the neck and reduce the frequency of healthful pulling actions for the brain. It is naturally expected that inflammation caused by this posture in the neck will directly cause damages to major arteries and spinal cord. To maintain health, one would need to do more exercises with aging to help maintain neck health. However, this lifestyle will DRAMATICALLY move this imbalance in an unfavorable direction. This impact can take very long time such as five, ten, to several decades to materialize. When things become bad, ordinary people will not be able to recover by using medical methods. For people with special exercise skills, it can be a long battle for recovery.

The forth reason is the adverse effect caused by reduced exercises. This reason is based upon my own theory which cannot be challenged. Based on my own experience and a large number of medical miracles, I found that doing exercises is the most effective means for re-training the brain (the theory is very long). When the cell phone life style is replacing minimum exercises in the U.S., it will have huge adverse health impacts. It will take time to show the adverse impacts. 

One biggest health problem is tinnitus. Due to the use of excessive sound, compromised vascular systems, and neutron usages imbalance, tinnitus will rapidly increase. Curing tinnitus is an extremely hard battle while modern medicine just cannot help a lot. It is one of the worse plains that many people will suffer as the worst life experience they can ever remember.

Bad lifestyles advocated by money-driven medical professionals is another reason. Now, it is widely believed that nutritional supplements will give health. It is absolutely good to use them to fix an obvious nutritional imbalance by a short term use. However, the media has misled the population to believe that it is a way of life. I must say it is a way of health destruction. The great nutritional imbalance caused by abusive long-term use of nutritional supplements can seriously damage organs, the central nerve system, and the vascular system. It is natural that many people will suffer severe mental disorders when they are old. When people cannot lesson, I feel hopeless.

The extremely bad lifestyle in this social media age will ruin many people life even though it is obvious now, but politicians and medical doctors are still in dark. I hope the public needs to understand that population health is under destruction with a huge momenta. For such a huge complex system, there is no way to stop or reverse it. It just keeps ruining people life and they will never know why.

Mental diseases are only a small part of future health problems. I have made a campaign on stopping the destruction of population health, but the U.S. is unable to stop and reverse the trend of population infertility?. I hope that media will do a right thing to save people life.
8
9
 
1
2
Remote Impacts of Qi and Sensitivity
3 4 5
6
7
In Qigong literature, some practitioners claim that they experienced all kinds of strange phenomena. Some of such claims are clearly fraudulent while others may be exaggerated. However, I will point out a few things that I personally experienced and can be justified from scientific basis.

(1) The remote impact of Qi.

This is one phenomena that can be explained by considering waves penetrating effects. Qi is just a total life energy that includes electrical signals, sound waves, nerve signals, thermal energy, etc. Each of them can affect tissues and cells in the vicinity. Thus, I believe that Qigong master can use their hands to treat diseases on another person. However, the real problem is that Qi can reach only a short distance. A claim that one can treat diseases at a very far distance is probably exaggerated. Moreover, external Qi would show real effect after a long term use. It must be sufficient long and intense to change tissue cells populations by affecting stem cell differentiating behaviors. So, it could need a long term treatment, and hard work to see a real result.

(2) Qigong practitioner's sensitivity in detecting inner part

For years, I have double on all claims that some people have extreme sensitivity on detecting inner body. Now, I have to hold an open mind due to my recent finding that I can detect my own pulse in my finger only when I am in extremely meditation condition. 

When I used my finger to massage a subject in an attempt to get rid of a growth (it is a on-going experiment), I circulate Qi on my finger. I and the subject could feel the pulsing sensation. For years, I thought it is a common phenomenon. However, I recently found that the pulse rate I detected from my finger tip is exactly same as what I detected for my heart beat. When I stopped circulating Qi, I cannot detect anything. This implies that when I am in a deep meditation state, the point of focus would have increased pulse intensity and have a higher sensitivity. This is important to say that people can dramatically improve sensitivity for detecting inner body by deep medication. This also implies that the brain might have a better ability to sense where the focus is.

I justify the increased sensitivity from other sensory systems. Vision, hearing and smelling sensitivities in humans are extremely high. Those sensing methods are routinely used with high focus. However, toughing is not well used with focus. Most people do not even use them. Thus, when one focuses attention to a finger, its sensitivity can be increased dramatically.
8
9
 
1
2
Adverse Health Effects of Grilled Foods
3 4 5
6
7
People from every culture loves grilled foods. This might be due to that human used fires in the long evolution. Grilled tastes is what people love. In Chinese culture, very strong fire is used to make very delicious foods. In comparison, the grilled foods were loved by people. People like semi-burned food text as well as the taste from slighted burned foods such as meets.

Direct heat grilling can expose food to temperatures often in excess of 260 ?C (500 ?F). What the grilling can generate would depend upon the composition of foods and the temperature and duration of temperature, and interactions of food compounds in high temperature. The Maillard Reaction. This is a process that takes places, it?s responsible for the flavors in cooked meat, fried onions, roasted coffee, toasted bread, etc.

Grilled meat acquires a distinctive roast aroma and flavor from a chemical process called the Maillard reaction. The Maillard reaction only occurs when foods reach temperatures in excess of 155 ?C  or 310 ?F.

(1) Products of Mailard Reactions

In 1973, American chemist John E. Hodge published a mechanism for the different steps of the reaction, categorizing its stages and identifying a range of the different products produced as a result of these. He identified the first stage as being the reaction between the sugar and the amino acid; this produced a glycosylamine compound, which in the second step rearranged to produce a ketosamine. The final stage consists of this compound reacting in a number of ways to produce several different compounds, which can themselves react to produce further products.

The products of the Maillard reaction are bad. The carcinogenic compound, acrylamide, can also be produced as a result of the reaction, and the levels of it rise as food is heated for a longer period of time. Fast food contain particularly high levels of acrylamide though measures have since been taken to try and reduce these levels.

Studies have shown that cooking beef, pork, poultry, and fish at high temperatures can lead to the formation of heterocyclic amines, benzopyrenes, and polycyclic aromatic hydrocarbons, which are carcinogens.

Marination may reduce the formation of these compounds.[7] Grilling is often presented as a healthy alternative to cooking with oils, although the fat and juices lost by grilling can contribute to drier food.

(2) Products of thermal decomposition

Many compounds can decompose to yield different products. Although most compounds decompose at very high temperatures, there are some compounds that can decompose at grilling condition. In the vicinity of fire striking point, the temperature can reach. For example, butane in air can reach 1970 ?C  or 3578 ?F), wood in air 1980 ?C or 3596 ?F (normally not reached in a wood stove), acetylene in air can reach 2550 ?C or 4622 ?F, and methane (natural gas) in air 1950 ?C or 3542 ?F.

The decomposition temperatures of compounds vary. They generally depends upon the chemical bond strength. Weak bonds can be broken more easily that strong bonds. For metal compounds, their decomposition temperatures depend upon their position in reactivity series.  Metal atoms at the top of the reactivity series form stronger bonds, and strong bonds can withstand higher temperature. In contrast, for the metals near the bottom of the reactivity series, their compounds generally decompose easily. For example, copper sulfate begins to decompose at about 200 ?C but potassium sulfate does not decompose at its melting point of about 1069 ?C, nor even at its boiling point. Foods must be viewed as a complex mixture of metal compounds, natural compounds, proteins, fats and carbohydrates. 

Grilling can generate high amount of free radicals. Because meat contains fats, which can be oxidized when cooked at high temperatures. The iron that exist in meat can also become oxidized. Preservatives used in processed meats such as sausages, bacon, ham, pepperoni, hot dogs, salami, corned beef, deli meats, etc. may generate free radicals. Free radicals can damage cells in the body.

3. Toxic compounds from Woods, coals, and other burning materials.

In some grilling setting, thermal decomposing products would depend upon burning materials used. Many of the decomposing materials are harmful. While they are released from the burning materials, they can get into foods over the hire flame. 

4. Truth Health Impacts

Many studies have been done to understand carcinogenics impacts. The true impacts on health and longevity are not known. Because modern medical research relies upon a population-based approach and attempts to determine effects crossing nine big factors, it is unable to determine the truth harmful impacts. I can show elsewhere that those compounds may be responsible for lower human lifespans by great margins. There are two main reasons for making this assertion: most of the decomposed products are not present in food, water and air in most part of the long evolution. Second, many of thermal decomposed compounds are obviously toxic to cells. Thus, they can damage cells in a long run even though their impacts cannot be detected or measured.

I induced from the facts we know that long term impacts of thermal decomposed products are realized by damaging cells and cell apparatus. It is known that damaged and abnormal cells can be repaired by stem cells. Stem cells can differentiate themselves to become replacement cells.  Thus, such damages cannot be detected easily and give a false impression that all such compounds are harmless. Second, those products may affect personal health by impairing Qi levels (like life energy). My theory is that many of a large number of thermal decomposed products can impair one or more enzymes in the body. They may slow down energy metabolism in organs, tissues, etc.  When energy metabolism is impaired, the Qi level will go down. Another possible problem is that some decomposed products may disturb normal metabolic balance. Some biochemical processes may proceed too faster while others may go too slowly. While those effect is harmless if they happen only rarely without lasting a sufficiently long time. 

Most products may reduce the Qi level in the body. I believe this will have a profound impact on health through influencing stem cell differentiation behavior. When the Qi level in any tissue or organ degrades, the new cells that are generated by stem cells will be like those cells. If the Qi keeps degrading with time, the biological activity of the cells in the tissue or organ will also keep degrade. Even though a person can live even at a fraction of the organ function, deteriorating effects of thermal decomposed products must be an important factor of cutting human lifespans. When the body or organ Qi level is kept to degrading on a long term basis, it will generate an tissue condition where the stem cells can generate like cells. In other words, the stem cells are unable to generate normal cells. Thus, the body, the organ or tissues lose biological activity faster than humans who are not exposed to those products.  I am very comfortable about my hypothesis, given the huge number of discoveries in stem cells research.  

The best way of avoiding adverse health impacts of thermal decomposed compounds is to avoid using grilled foods and foods that are exposed to high temperatures. If you must eat grilled foods, you should avoid using very high temperature and direct contact with fire frame. You should avoid using unclean and toxic burning materials or other materials that could generate really toxic products. Finally, you may consider using protective foods together with grilled foods. For example, you may use fresh foods containing high contents of vitamins C, E, A, etc. to protect cells and/or counteract with the deteriorating effects of thermal decomposed products. 
	
8
9
 
1
2
The Human Body Is An Open System
3 4 5
6
7
Life is both an automatic system and also an open system. It must continuously exchange material, energy and information with the external environment.

The human body is OPEN to the world. Nearly all non-traumatic acquired diseases are caused by disease agents crossing three open paths: the digestive track, all skin exposed to air and the lung alveoli, where gas exchanges take place. Pollutants and toxic compounds from food, water, and air get into the body from the digestive track; and harmful compounds and other disease agents can get into the body from the skin. Metabolic products from microbes in the lungs, the gut and the skin can easily get into the body. Substances that get into the body directly change physiological properties in the body. The two main perception channels are vision, hearing, smelling, and touching are less important. Perceiving shocking or harmful things can trigger harmful physiological reactions by hormone actions and signal regulations. 

Such an open system contains a large number of substances that are from foods, air, and water and distributed by the circulating blood and moving body fluid. Every substance in the open system can affect the physiological processes and biochemical reactions in any part of the body even though they are not reactants or products in the processes and reactions. Each substance can exert its effect by affecting fluid acidity, water activity/osmotic pressure, fluid pH, fluid viscosity, compound-compound interactions, physical absorption on tissue calls, inorganic balance, nutrition competition, nutritional balance (total calories balance, fatty-acid ratios, amino acid ratios, and mineral balance etc.), ionic strength, interference to cell functions by a large number of ways, interfere with molecular recognition mechanisms, interference with diffusion speeds of others, altering volume concentrations of other components, physical space effects, and interactions with nerve signals.

Any study attempting to treat human body as a close system is meaningless. All health problems must be treated as an open system.
8
9
 
1
2
Nine Big Factors Determines that the Best Approach to Wellness and Longevity Is Optimization Methodology
3 4 5
6
7
People differ in Nine Big Factors: races, personal genetics, age, sex, food, lifestyle, exposure to same disease agent, interactive compounds and health conditions. The differences are similar to those found in cars.

Size is closely related to genetic and food. Just the difference in the heart size between a 200 lb white and an 80 lb Asian woman can make normal blood pressure readings meaningless. Deviations among human beings are more than the deviations among all different cars. If one single combustion pressure standard is applied to all cars in the world, then most sports cars will be crippled, most small cars will blow out, and all performance cars will become lame ducks. If auto mechanics are required to fix cars according to two-binary standards, half of the cars will no run. Dead cars will be found all over places. 

Look at all people in a class room, a working place, a store or any place to determine how they differ. It is absolutely absurd to attempt to treat all of them as same in studies and then use population data and population-based findings to individuals.

If this methodology were used in car repairs, all mechanical problems in cars would become "incurable".
8
9
 
1
2
A Short Introduction to Chinese Medical Theories
3 4 5
6
7
Chinese Medicine is an experience-based medicine, which has been used for more than four thousand years. Even though it was established very early, it is very similar to Optimization Methodology used in science. The soul of its teachings is relative, holistic, and dialectic approaches while it treats human body as an open system with its focus on emotion and mind. The model is the best we can imagine and that is why it can cure chronic diseases.
8 Chinese-medicine-introduction.pdf
9
 
1
2
Disease Agents' Risk Cumulative Theory
3 4 5
6
7
We proposed a risk cumulative principle (Risk Cumulative Theory). There are tens of thousands of things that are harmful to our health, but we cannot prove any of them by using controlled trials. We note that there is no good method for discovering the effects of harmful effects that take a long time to realize. A large number of harmful things may be found in foods, drinks, lifestyle, environment, and job sites. Each of them may add risk of injuries by a tiny bit. Many of them are too small to be determined as harmful disease agents. If a person accepts risk from a large number of disease agents, the person will get injured by multiple-unity probabilities (one for one disease) (there would be multiple probability spaces in probability).

Risks from disease agents can be accumulated in three ways: (1) same or similar disease agents can cause damages to the body by repeated exposures in different times, and thus damages can be accumulated in their life times; (2) different disease agents can cause similar damages which are cumulative in their adverse impacts on the body functions; (3) different disease agents can cause different damages with different impacts on different body functions, and thus causing different diseases; and (4) damages to a large population caused by all disease agents are the sum of all damages to individual persons, and are presumed to be gigantic in magnitude. In contract, other factors such as genetics, age, sex, and health conditions are not cumulative. It is wrong to allow those non-cumulative factors to hide the true effects of mild and slow-working diseases agents.

In other words, a person will get not just one injury, but several injuries in his or her life time. The risk is cumulative in multiple dimensions. The probability of injuries is summed for all disease agents in each year and summed up for all years. This is a reason for a person to have multiple diseases in his entire life.
8
9
 
1
2
Multiple Random Factors Disease Reversal Theory
3 4 5
6
7
Wu and Zha (2017) proposed this theory (?Quantitative disease causes reversal theory?) when they are writing this book. This theory may be referred to as quantitative disease reversal theory. This theory is an application version of the holistic principle that has been known for more than 4000 years. It is used to cure diseases in a concrete way for the first time.

We have pointed out that the human body is an open system. Any chemical compounds can get into the body and reach every cell in a matter of minutes to hours. The globalization and food sharing have completely changed the scope of exposure to food-born disease agents. In any one day, a typical American might be exposed to chemicals compounds, toxins, pollutants and other materials from several to tens other nations. Air-bone disease agents are also shared by the all people in the planet. For example, Japanese radiation-polluted air has long reached the U.S.; the radioactive ashes from U.S. must have reached other nations; and polluted air in China must have reached the U.S. Information can be a primary disease agent of mental and emotional diseases. The internet has changed the scope of its reach and the speed of its reach. A person can be harmed by any unwelcome information or sad and harmful news about their family members and friends in remote places. A person can be found all over the places in just one week. All health properties of human beings are affected by a gigantic number of diseases agents on the planet. Thus, human body has become an extremely open system that no science has ever studied in a systematic way. It is impossible to find the types and amounts of disease agents a particular person has been exposed to.

This extreme openness nature and constant material exchanges, energy exchanges, and information changes determine that no duplicate and distinctive disease mechanisms can be found and that health problems cannot be studied by using controlled methods which are good for closed systems. In treating diseases, any methods based upon closed systems will not work on real people in most times and all generalized methods based upon population studies are meaningless.

Based upon our Multiple Random Factors Disease Causes Theory, the practical inability to control exposure to disease agents, and impossibility to know prior exposed disease agents, there is no way to identify one or more cause factors for any patient in treating a disease. Moreover, multiple cause factors tend to present in a super majority of patients. Even if a disease is triggered by an initial cause factor, a large number of other factors will soon become contributing cause factors. Moreover, there is no way to fix functional and structural problems directly (note surgery is not applicable to most chronic diseases). Thus, we must conclude that the most rationale and only workable treatment method is to use all potential cause factors to change physiological properties of diseased tissues in order to reverse the disease.

Hundreds of factors can make different-amount contributions to high blood pressure, and thus one cannot just stare at one or two factors in reversing the disease. While a population study shows one, two or a few factors or certain patterns, conclusions in the studies are not applicable to any particular person in the study or anyone in the general population. Legal rule can be imposed on anyone, but health parameters cannot. Data from other persons cannot be used to treat a specific person. Readers can understand our theory by reading our long analysis of the quantitative disease causes model for high blood pressure.

A common-law tradition is to make everything as simple as possible often for the convenience of judges, but such a simple approach will not solve real problems. It cannot be applied to all other walks of life. Health data such as medical practice guidelines, liability law, hospital regulations, and doctor regulations are developed on basis of population data and generalization, and cannot be used to cure individual diseases. Those regulations would prevent doctors from doing anything that could cure diseases. Modern medicine will never succeed by using such an oversimplified approach: treating all patients suffering a common disease by using same methods.

As we stated above, exposure to disease agents in such an extremely open system cannot be known in a future time (with rare exceptions). The disease cause factors for one person will never be the same as those for others in both quantitative and qualitative scales. In addition, contributions of genetic and lifestyle factors cannot be ascertained with any reliability in real cases and treatment methods for model studies cannot be used in real life. Using averaged data or population data is the worse attempt which will inflict more harm than good. This means that the notion of treating same disease by same method must be abandoned....
8
9
 
1
2
Multiple Random Factors Disease Causes Theory
3 4 5
6
7
Wu and Zha (2017) proposed this theory (?Quantitative disease causes theory?) when they wrote this book. It is intended to be a new foundation for treating future diseases. This theory may be referred to as quantitative disease causes theory.

Each chronic disease is caused by a large number of unpredictable and random factors as disease causes. As shown in the causes for high blood pressure, hundreds of factors can contribute to an elevated blood pressure. Many of the factors are unpredictable and highly dynamic because they may be present in some cases but absent in other cases. All of the factors are random variables: they make contributions to the disease in a quantitative manner. Any factor can contribute nearly zero, a tiny little bit, a little bit, some, a lot, a great deal, or nearly all of disease-causing effects to the disease, just like a random variable defined by a bell with two long tails. This theory is applicable to any chronic disease. Each of causal factors makes a quantitative contribution to the disease.

All diseases are caused by changes in physiological properties (?ΣPP?) in the body or relevant tissues. Physiological properties may also be referred to as ?physiological environment? or ?chemical environment? when it is referenced relative to a special subject such as a tissue or an organ. Physiological properties (?ΣPP?) in a tissue are defined by all present compounds, all structural cells in the tissue, all mobile cells, pollutants and foreign agents, remaining metabolic products, etc. Physiological properties are greatly influenced by circulating blood and tissue fluid. Physiological properties in a tissue depends upon, among others, nutrients, water activity or osmotic pressure of the liquid phase, compound concentrations and their gradients, fluid acidity, cell health conditions, their physiological and biological activities (enzymes and other biological molecules), and nerve signals from the brain or other organs. Physiological properties are related to tissue vitality, Qi level (or external signals for stem cell differentiation), inflammation driving force and tissue repairing mechanisms.

Anything that can permanently cause changes in the physiological properties of a tissue or organ or the whole body can make a contribution to one or more diseases. Different set of factors may result in different physiological properties, thus causing different diseases. All known disease agents create diseases by influencing physiological properties. Long-term abuse of nutritional supplements may result in next national health crisis because the extreme high concentrations used in a long term basis can disturb physiological properties of the body.

In a tissue, all physiological processes and biochemical reactions take place in an open system. This openness nature was known more than 1700 years ago. Such an open system contains a large number of substances that are from foods, air, and water and distributed by the circulating blood and moving body fluid. Every substance in the open system can affect the physiological processes and biochemical reactions in any part of the body even though they are not reactants or products in the processes and reactions. Each substance can exert its effect by affecting fluid acidity, water activity/osmotic pressure, fluid pH, fluid viscosity, compound-compound interactions, physical absorption on tissue calls, inorganic balance, nutrition competition, nutritional balance (total calories balance, fatty-acid ratios, amino acid ratios, mineral balance, etc.), ionic strength, interference to cell functions by a large number of ways, interfere with molecular recognition mechanisms, interference with diffusion speeds of others, altering volume concentrations of other components, physical space effects, and interactions with nerve signals.

The central nerve system is a super sensitive system that can detect any change in Qi in the tissue. Even an inactive compound can change microwaves, infrared, electronic absorption profile, sound profile, cell motions, pH, water activity, osmotic pressure, dipole movements, etc. The absorption and emission waves (at different temperatures) and physical activities can interact with nerve signals, and the Qi from the tissue superimposes on nerve signals sent to the brain. The brain thus is able to decode the nerve signals retrieve the information originally carried in the Qi, and thus understands the physiological properties of the tissue. In response, the brain sends regulatory signals to the tissue consistent with the state of the tissue.

Therefore, one cannot treat the human body as a closed chemical reactor where reactants and other chemical compositions can be controlled and everything else can be ignored. This reality dictates that a disease cannot be cured by working on only one, two or a few reactants or compounds....
8
9
 
1
2
The Main Features of Health Optimization Method
3 4 5
6
7
We propose a new approach for achieving personal health by using Health Optimization Methodology (HOM). This is the only way to achieve personal long-term health. This method is formed to correct the improper basic model, diagnosis method, and flaws in the basis research. Its main features includes following aspects:

(1) Treat the human body as an open system, which is directly contrary to the controlled method.

(2) Always consider all potential variables and their interactions, in direct conflict with the controlled variable methodology used in modern medicine.

(3) All health methods must be optimized against multiple health target criteria. For example, in evaluating a drug's treatment of an infection, one must consider how it affects other health properties such as kidneys. A diet to lower heart attack risk must be judged for its potential impacts on overall death rate.

(4) Reject the notion of using controlled studies because such studies are incapable of finding long term impacts.

(5) This method naturally avoids averaging data cross individuals. In the U.S., people variations in health properties are more than those of cars. We view summing and averaging data across make and models as wrong practice that would ruin most cars if such data are used as car repairing guidelines. Our optimization method does not consider any influences of other people's health parameters. It is only a time-progressive optimization.

(6) When health care attention is directed to the same person, potential variables are reduced to only substances that might enter into the body from food and air. In this case, controlling variables is realistic.

(7) However, a difficulty is attributing achieved health results to a particular treatment. This is not important to the patient. Our focus is not on possibility to explore successful method. Besides, accurate identification of a successful treatment is useless in the real world because every person lives in an open system.
8
9
 
1
2
Slow Diseases Reversal Speeds
3 4 5
6
7
Wu proposed this theory (Wu's third disease theory) in 2001. Most, if not all, chronic diseases progress slowly.
Disease factors affect human health like footsteps injuring a floor by wears and tears. If a floor has been used for 50 years, it may be severely damaged by wears and tears. Every foot step on the floor has contributed to the wears and tears. Moreover, any other factors such as mechanical contact, abuse, biological attacks, and chemical attacks are contributed to the wears and tears. Another model is grounding a steel rod into a needle. Reversing a disease is like grounding a steel rod into a needle. This is a best way to tell how much time one may need to make a change in most situations.

As implied by the model, a disease develops very slowly. Disease effect generally cannot be studied by using a controlled study in a normal clinic setting. The only way to address this kind of slow effect is system modeling and theoretical method. Since a large number of disease cause factors have cumulative effects, it is improper to use a method which is suitable for a chemical reactor.
As we have stated for our disease reversal theory, it is impossible to tell whether a particular measure is working based on incremental improvements of condition. Due to the impossibility to identify cause factors and a long-time lag between changes in physiological properties and disappearance of symptoms, it is impossible to determine which measure is working or which measures are not. Therefore, treatment measures should be formulated in a multiple factors approach. Patients should understand that fast fixes (such as pain killers, sedative drugs, and symptom controllers) cannot cure diseases. True cures such as exercises, well designed diet, lifestyle changes, and traditional methods always work slowly. It is often a mistake to stop measures because patients could not see improvements in a time scale of fast fixes.

We presume that all disease effects are permanently left on human body no matter how small each individual effect is. If we accept the cumulative effect model, we cannot just look at the effects of the last footstep on the floor and ignore millions of prior footsteps.
The time scale of chronic disease development is one to fifty years. For example, atherosclerosis may take 10 to 40 years to develop. Many types of cancer take more than 5 years; and most drugs site-effects take many years and many rounds of uses to show up. It is impossible to study how each of disease factors affects disease process. So, findings of some causes in controlled studies are a matter of luck. Most studies can not be construed to exclude other cause factors, and most findings from controlled studies cannot be applied to individual persons.

Healing a disease is also a very slow process just like development of the disease. Reversal of a chronic disease cannot be achieved in a time scale that a drug is used to control symptoms, sedate a person or stop pain. There is a well known say that ?diseases comes like mountain collapsing, and go like moth producing silk strands.? This famous Chinese saying reflects the nature of all real diseases. A disease takes a long time to develop before the ?collapsing of a mountain?, and also requires a long time to heal.
If a disease is found in a sufficiently early state, virtually any of a large number of methods can help reverse or at least stop its progress. However, in reality, few people are able to achieve it. The real reason is that people have gotten used to fast fixes and comfort medicines so that they could not see real cures. Both doctors and patients expect that cures could take effect like pain killers, sedative drugs or symptom controllers. All treating methods including massages, inductive massage, point massage, exercise, deep breathing exercises, and relaxation can be highly effective to get rid of diseases, but a super majority of people will try them a few times, a few days, or a few months, and quickly abandon them. Due to influences of quick fixes, the people in China start abandoning the most powerful healing methods that have used by generations of people in more than four thousand years.

However, successful herb treatment cases and the advancement of the stem cell research suggest the existence of fast cures for reversing certain chronic diseases. Unfortunately, cures using such technologies are very remote from application. We also expect that in order to trigger stem cells to replace diseased, mutated and non-functional cells, it is necessary to cause additional injury to the tissue or create tissue signals (e.g. ?external signals?) in the tissue. Creating that condition may be a big risk. Greatest cures come with highest risks.
8
9
 
1
2
A Quantitative Disease Causes Model
3 4 5
6
7
We propose a quantitative model for causes of chronic diseases and some acute diseases. This model clashes with the presumption that a disease is normally caused by a simple disease mechanism. Here, we will show how Wu's disease theory is used to address high blood pressure. We will use high blood pressure as an example to show our quantitative disease causes model.

 Blood pressure is controlled by the central nerve system and also depends upon terminal flow resistance. Based upon direct observation, we propose that high blood pressure is a quantitative function of a large number of random, dynamic, and mutually-interactive variables. Each of the variables is also a basic cause factor. All factors are dynamic in that they may be present or absent in specific case, they are all random in that they can take different quantitative contributions. Most of the factors can interact with other factors, and can interact with the structures of organs and body parts, and physiological processes.

To a great extent, blood pressure is a quantitative concept, despite the strange notion that blood pressure can be divided into normal and abnormal values. The two status scale was extended from the ancient ruling principle that everything was rated by two statuses. Criminal law, for example, divides all people into criminal and non-criminal. We find that the binary standard makes no sense in health, which follows natural law but will obey any imposed rule.

We will show our theory by using hypothetical persons. We have a person who has basic blood pressures 100/70. The person gradually blocks the capillaries by adding one gram fat net deposit on the blood vessels per day. Then, blood pressure will progressively increase. To maintain the same blood flow to meet the energy demand, the heart must pump harder and faster. The blood pressure will increase gradually. If the person gets a fatty liver which further impairs his blood circulation in the liver, and this will increase flow resistance a little bit (ignoring consequential impact caused by the liver diminished functions on the whole body). If this person gets a chronic kidney disease which results in blockage of more capillaries in the kidneys, the new blockage also increases his blood pressures by further increasing flow resistance. If the person gets diabetes, a further increased glucose levels will further block blood vessels, and thus further increases the blood pressure. Blood pressure in the person rises quantitatively little by little. The nature of blood pressure is not a binary human action of doing or not doing something or a commercial transaction of selling or not selling something.

To find a cure for high blood pressure, one has to reduce flow resistance quantitatively. It is not a problem that can be solved only by addressing one thing even though one or more factors have large contributions to the high blood pressure. Blood pressure can be lowered by doing a large number of things, and can be lowered by different degrees by working on each thing. It can be reduced by expanding some of the blood vessels or by expanding blood vessels in different degrees. It can be reduced by removing fats from inside walls of any and all of the blood vessels, reducing blood viscosity, and increasing amount of oxygen carried in the blood. Blood pressure can be reduced by improving the kidney function for removing metabolic wastes. Except in rare cases, high blood pressure is not a disease that can be fixed by addressing one single factor according to two binary values (except in rare cases where high blood pressure is caused primarily by one single factor). For most high blood pressure patients, cures must be designed according to the holistic principle and address all contributory factors.

Now, let us consider dynamic changes of blood pressure, we see the same quantitative nature. An increased blood pressure is normally caused by an increased demand for energy. All different activities will require the heart to increase output in a quantitative way. A drop in the glucose level, deprivation of oxygen, degradation of blood health composition will cause the heart to increase beat rate. Each of those changes takes place in a quantitative way. None of them take binary values. Virtually anything, including lost muscle force by damaged nerves, lost or blocked capillaries, and inflammation in any organ can cause the heart to raise blood pressure quantitatively.

All properties in blood pressure-regulatory mechanisms are also quantitative. All actions prompting higher heart outputs increase blood pressure in quantitative ways. The needs to trigger hormone actions do not depend upon the binary rule. The demand is also quantitative. All actions take place with different forces and thus are quantitative. When more and more capillaries are blocked or narrowed, flow resistance increases, and less energy target tissues or organs can get, the body demands higher heart outputs.
8
9
 
1
2
Use Instructions
3 4 5
6
7
Each of the tab is configured to accept files and data records. All files are can be accessed by using the Red_No. Anyone can add files to this database but the owner retains right to approve or disprove. 
8
9
 
1
2
What Is Health Optimization Engineering?
3 4 5
6
7
This database is for collecting deep analysis by using Health Optimization Method. Optimization method is like auto mechanic repairing cars. They fix problems by looking at individual car. This is in shape contrast to population-based medicine, which uses control studies for the population. Modern medicine is actually population-based: It collects data from the population and then applies the data to individual persons. It is obvious that if cars are repaired by using such a population approach, most cars will be crippled, damaged, or destroyed. 

That is how the wrong medical model has screwed most people health and results in incurable diseases. The notion cannot stand against the massive number of medical miracles.

That is a fundamental difference. Health optimization methodology is used to achieve highest system performance and the longest lifespan.
8
9